Bessie is an English diminutive of Elizabeth, and as such has been used since the 16th century. Bessie is sometimes used as an independent name.

Bessie may refer to:

* Bessie (lake monster) — a lake monster in lake Erie. * Bessie Smith — blues singer. * Alvah Bessie — screenwriter blacklisted as part of the Hollywood Ten. * Diamond Bessie — a murdered prostitute. * Bessie Coleman — first African-American female aviator. * Bessilyn Johnson — the woman who inspired Scotty's Castle. * In the science fiction television series Doctor Who, Bessie was the third Doctor's souped-up yellow Edwardian roadster. * In popular culture the name of a cow. * Bessie is also the name of an asphalt-paver in the movie Cars.

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